Prehospital Delay in Patients With Acute Coronary Syndromes (from the Global Registry of Acute Coronary Events [GRACE])
Identifieur interne : 008153 ( Main/Exploration ); précédent : 008152; suivant : 008154Prehospital Delay in Patients With Acute Coronary Syndromes (from the Global Registry of Acute Coronary Events [GRACE])
Auteurs : Robert J. Goldberg [États-Unis] ; Frederick A. Spencer [États-Unis, Canada] ; Keith A. A. Fox [Royaume-Uni] ; David Brieger [Australie] ; Ph. Gabriel Steg [France] ; Enrique Gurfinkel [Argentine] ; Rebecca Dedrick [États-Unis] ; Joel M. Gore [États-Unis]Source :
- The American journal of cardiology [ 0002-9149 ] ; 2009.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Duration of delay in seeking medical care in persons with symptoms of evolving acute myocardial infarction (AMI) is of current interest given the time-dependent benefits associated with early use of coronary reperfusion approaches. The objectives of this multinational study were to describe geographic variation in the extent of and factors associated with prehospital delay in patients enrolled in the GRACE study. Data were collected from 44,695 patients hospitalized with an acute coronary syndrome in 14 countries from 2000 to 2006. The regions under study included Argentina and Brazil (n = 8,203), United States/Canada (n = 12,810), Europe (n = 19,354), and Australia/New Zealand (n = 4,328). Patients with ST-segment elevation AMI, non-ST-segment elevation AMI, and unstable angina comprised the study population. There were marked geographic differences in extent of prehospital delay in patients with ST-segment elevation AMI and those with non-ST-segment elevation AMI/unstable angina. In patients with ST-segment elevation AMI, the shortest duration of prehospital delay was observed in patients from Australia/New Zealand (median 2.2 hours), whereas patients from Argentina and Brazil delayed the longest (median 4.0 hours). Median duration of prehospital delay was shortest (2.5 hours) in patients with ST-segment elevation AMI, whereas patients with non-ST-segment elevation AMI/unstable angina showed considerably longer prehospital delay (3.1 hours). Several demographic and clinical characteristics were associated with prolonged delay overall and in the different geographic locations under study. In conclusion, results of this large multinational registry provided insights into contemporary patterns of care-seeking behavior in patients with acute coronary disease.
Affiliations:
- Argentine, Australie, Canada, France, Royaume-Uni, États-Unis
- Massachusetts, Nouvelle-Galles du Sud, Ontario, Écosse, Île-de-France
- Hamilton (Ontario), Paris, Sydney, Édimbourg
- Université McMaster, Université d'Édimbourg
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Le document en format XML
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Spencer</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Department of Medicine, McMaster University</s1><s2>Hamilton, Ontario</s2><s3>CAN</s3><sZ>2 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université McMaster</orgName></affiliation></author><author><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A. A." last="Fox">Keith A. A. 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Goldberg</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Spencer, Frederick A" sort="Spencer, Frederick A" uniqKey="Spencer F" first="Frederick A." last="Spencer">Frederick A. Spencer</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Department of Medicine, McMaster University</s1><s2>Hamilton, Ontario</s2><s3>CAN</s3><sZ>2 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université McMaster</orgName></affiliation></author><author><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A. A." last="Fox">Keith A. A. Fox</name><affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Cardiovascular Research, Division of Medical and Radiological Sciences, The University of Edinburgh</s1><s2>Edinburgh</s2><s3>GBR</s3><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Coronary Care Unit, Concord Hospital</s1><s2>Sydney</s2><s3>AUS</s3><sZ>4 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Gabriel Steg, Ph" sort="Gabriel Steg, Ph" uniqKey="Gabriel Steg P" first="Ph." last="Gabriel Steg">Ph. Gabriel Steg</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Département de Cardiologie, INSERM U-698, Université Paris 7, AP-HP</s1><s2>Paris</s2><s3>FRA</s3><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Gurfinkel, Enrique" sort="Gurfinkel, Enrique" uniqKey="Gurfinkel E" first="Enrique" last="Gurfinkel">Enrique Gurfinkel</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>ICYCC Favaloro Foundation</s1><s2>Buenos Aires</s2><s3>ARG</s3><sZ>6 aut.</sZ></inist:fA14><country>Argentine</country><wicri:noRegion>ICYCC Favaloro Foundation</wicri:noRegion></affiliation></author><author><name sortKey="Dedrick, Rebecca" sort="Dedrick, Rebecca" uniqKey="Dedrick R" first="Rebecca" last="Dedrick">Rebecca Dedrick</name><affiliation wicri:level="2"><inist:fA14 i1="07"><s1>Center for Outcomes Research, Division of Surgery, University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Gore, Joel M" sort="Gore, Joel M" uniqKey="Gore J" first="Joel M." last="Gore">Joel M. Gore</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School</s1><s2>Worcester, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j" type="main">The American journal of cardiology</title><title level="j" type="abbreviated">Am. j. cardiol.</title><idno type="ISSN">0002-9149</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The American journal of cardiology</title><title level="j" type="abbreviated">Am. j. cardiol.</title><idno type="ISSN">0002-9149</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute</term><term>Acute coronary syndrome</term><term>Cardiology</term><term>Circulatory system</term><term>Coronary artery</term><term>Coronary heart disease</term><term>Delay</term><term>Human</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cardiopathie coronaire</term><term>Retard</term><term>Homme</term><term>Aigu</term><term>Artère coronaire</term><term>Appareil circulatoire</term><term>Cardiologie</term><term>Syndrome coronaire aigu</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Duration of delay in seeking medical care in persons with symptoms of evolving acute myocardial infarction (AMI) is of current interest given the time-dependent benefits associated with early use of coronary reperfusion approaches. The objectives of this multinational study were to describe geographic variation in the extent of and factors associated with prehospital delay in patients enrolled in the GRACE study. Data were collected from 44,695 patients hospitalized with an acute coronary syndrome in 14 countries from 2000 to 2006. The regions under study included Argentina and Brazil (n = 8,203), United States/Canada (n = 12,810), Europe (n = 19,354), and Australia/New Zealand (n = 4,328). Patients with ST-segment elevation AMI, non-ST-segment elevation AMI, and unstable angina comprised the study population. There were marked geographic differences in extent of prehospital delay in patients with ST-segment elevation AMI and those with non-ST-segment elevation AMI/unstable angina. In patients with ST-segment elevation AMI, the shortest duration of prehospital delay was observed in patients from Australia/New Zealand (median 2.2 hours), whereas patients from Argentina and Brazil delayed the longest (median 4.0 hours). Median duration of prehospital delay was shortest (2.5 hours) in patients with ST-segment elevation AMI, whereas patients with non-ST-segment elevation AMI/unstable angina showed considerably longer prehospital delay (3.1 hours). Several demographic and clinical characteristics were associated with prolonged delay overall and in the different geographic locations under study. In conclusion, results of this large multinational registry provided insights into contemporary patterns of care-seeking behavior in patients with acute coronary disease.</div></front></TEI><affiliations><list><country><li>Argentine</li><li>Australie</li><li>Canada</li><li>France</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Massachusetts</li><li>Nouvelle-Galles du Sud</li><li>Ontario</li><li>Écosse</li><li>Île-de-France</li></region><settlement><li>Hamilton (Ontario)</li><li>Paris</li><li>Sydney</li><li>Édimbourg</li></settlement><orgName><li>Université McMaster</li><li>Université d'Édimbourg</li></orgName></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Goldberg, Robert J" sort="Goldberg, Robert J" uniqKey="Goldberg R" first="Robert J." last="Goldberg">Robert J. Goldberg</name></region><name sortKey="Dedrick, Rebecca" sort="Dedrick, Rebecca" uniqKey="Dedrick R" first="Rebecca" last="Dedrick">Rebecca Dedrick</name><name sortKey="Gore, Joel M" sort="Gore, Joel M" uniqKey="Gore J" first="Joel M." last="Gore">Joel M. Gore</name><name sortKey="Spencer, Frederick A" sort="Spencer, Frederick A" uniqKey="Spencer F" first="Frederick A." last="Spencer">Frederick A. Spencer</name></country><country name="Canada"><region name="Ontario"><name sortKey="Spencer, Frederick A" sort="Spencer, Frederick A" uniqKey="Spencer F" first="Frederick A." last="Spencer">Frederick A. Spencer</name></region></country><country name="Royaume-Uni"><region name="Écosse"><name sortKey="Fox, Keith A A" sort="Fox, Keith A A" uniqKey="Fox K" first="Keith A. A." last="Fox">Keith A. A. Fox</name></region></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name></region></country><country name="France"><region name="Île-de-France"><name sortKey="Gabriel Steg, Ph" sort="Gabriel Steg, Ph" uniqKey="Gabriel Steg P" first="Ph." last="Gabriel Steg">Ph. Gabriel Steg</name></region></country><country name="Argentine"><noRegion><name sortKey="Gurfinkel, Enrique" sort="Gurfinkel, Enrique" uniqKey="Gurfinkel E" first="Enrique" last="Gurfinkel">Enrique Gurfinkel</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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